Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency
Caitriona McLean*, Catherine M Greene*, Noel G McElvaneyRespiratory Research Division, Dept.Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland; *Each of these authors contributed equally to this workAbstract: Alpha-1 antitrypsin (A1AT) is a 52 kDa serine protease inhibitor that is syn